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Steady Improvement in Techniques for the Analysis of Degraded DNA

by Douglas Ankney

DNA, while remarkably resilient, may be degraded by exposure to ultraviolet radiation, extreme temperatures, humidity, and microbial activity. These exposures may result in “single-strand and double-strand breaks, depurination, deamination, and crosslinks.” Consequently, the DNA “becomes fragmented, diminishing its suitability for traditional forensic analysis methods that rely on ...

 

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